Spring 2008 Syllabus
Genetics Labs 212.L01 & 212.L03
R. T. Dillon

Readings are from my Genetics Laboratory Manual, available at the bookstore.

Date Topic & Exercise Readings
Jan 15, 16
Introduction  -
Jan 21*, 22
Probability & Statistics Inv. 1
Jan 28, 29
Drosophila familiarization 
Set up two experiments with the "Lobed" gene: 
 - A comparison of variation in expressivity due to 
    genetics and environment ("expressivity") 
 - Incomplete penetrance in a monohybrid cross ("penetrance")
Inv. 3 
Inv. 4
Feb 4, 5
Independent assortment and gene interaction in maize
Set up selection & drift experiments ("S&D") 
Clear penetrance & expressivity experiments
Inv. 2 
Inv. 5
Feb 11, 12
Set up trihybrid cross for gene mapping experiment ("THC") 
Analysis of variable expressivity 
Clear S&D experiments
Inv. 6 
Inv. 4
Feb 18, 19
Count & transfer F1 from S&D experiments 
Clear penetrance experiment 
Clear parentals from THC
Inv. 5
Feb 25, 26
Analysis of incomplete penetrance in a monohybrid cross
Make THC test cross 
Clear S&D experiments
Inv. 4
Mar 3, 4  (Spring Break) -
Mar 10, 11
Lab Quiz
Clear F1 from THC
Count & transfer F2 from S&D experiments
Inv. 5
Mar 17, 18
Linkage analysis  Inv. 6
Mar 24, 25
Human karyotype analysis
Count & transfer F3 from S&D experiments
Inv. 7
Inv. 5
Mar 31, Apr 1
Chromatography of eye pigments 
Clear S&D experiments
Inv. 8
Apr 7, 8
Protein electrophoresis Inv. 9
Apr 14, 15
Count F4 and terminate S&D experiments
Selection and genetic drift
Inv. 5
Apr 21, 22
Lab Quiz  -

            * MLK Holiday.  See course policy.

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