Understanding Cellular Behavior Using Microfluidics
Laurie E. Locascio, Chief, Biochemical Science Division, NIST
3 Feb 2007
Recent developments in microfluidics have demonstrated the power of using microfluidics to manipulate and probe cells down to the single cell level. Our work in this area has focused on patterning mammalian cells in microfluidic systems and studying their growth and behavior as the environment changes. Very recently, we initiated a new multidisciplinary program that will allow us to link microanalytical tools developed at NIST with single cell analysis to obtain signatures of cellular behavior. This talk will describe our research in studying cells in microfluidics and will discuss ultralow volume techniques that will allow us to probe cellular response even when the analytes are present at very low concentrations.